McKay is abrassive, even towards Shepard and his fellow team members (hell, he kind of thinks all soldiers are dumb, that can be clearly seen in 'The Siege, part II' when he's annoyed that he's not in the meeting (and he really should be there!), especially since they come to him in the end anyway!)!
He's certainly not more abusive towards Sam than towards others!
So no, he's not mysoginistic!
Yes, he targets Sam - but not because she's a woman, he's feeling insecure because she is at least as smart as he is (hell, she is the one that shows up in his version of 'Grace' ('Grace under pressure') so he secretly admires her!)! Hell, a similar patern can be seen when he's working with his sister who is smarter and - in his mind (I happen to agree, but that's beside the point!) - is wasting her gift on raising brats!
Rodney is certainly not a woman hater! He doesn't target Teyla with stuff like that for example (he isn't exactly nice to her - but he also doesn't treat her like a macho-man would (eye candy, good for sex and otherwise worthless!)) - why? Because she doesn't threaten him, she may be stronger etc. but she doesn't have his scientific mind and brilliance!
ps: Note: I am certainly not a macho-man, hell Sam is still my favourite SG-Character
