Coming up with different, never before seen abilities, will probably be a problem, because there's been so many different movies/tv series/books/comics about mutants or genetically altered/advanced humans. I think any of the abilities are just going to end up being powers that have been done before, but just presented differently; either by toning them down and/or making them seem more concrete or practical(which is basically what they've been doing with almost all the Alphas I guess) Eventually they're going to have to move on from just the new Alpha of the week episodes and go more into what's going on a larger scale. That already seems to be happening a bit, and I hope that ends up being focused on a little more sometime soon.
Personally, it really doesn't bother me if I've seen a certain ability or plot before, as long as I find the characters, how they interact with each other, and how the story is presented interesting; so far I'm pleased with how the series is going.
